December 2014

New analysis of the SYMPLICITY HTN-3 trial of renal denervation to lower blood pressure highlights key factors that may have contributed to the unexpected outcome

A new analysis of an important trial of the blood pressure-lowering procedure, renal denervation, shows that the main results may have been affected by a number of confounding factors that partially explain the unexpected blood pressure responses in patients. The analysis, published in the European Heart Journal [1], identified factors in the SYMPLICITY HTN-3 trial, […]