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Monthly Archives: November 2010

Researchers find new target for stopping tumours developing their own blood supply: phase I trial shows first drug to inhibit ALK-1 receptor is safe and effective

Researchers have found that a newly developed drug, which is aimed at a particular receptor involved in the development of blood vessels that sustain tumour growth, is active in patients with advanced cancers and, in some cases, has halted the … Continue reading

Published Friday, November 19th, 2010 at 12:01 am
Posted in Cancer, Genetics

Cough medicine could help doctors identify how breast cancer patients metabolise tamoxifen, enabling them to improve individual treatments

Cough medicine could be used as way of predicting how well individual patients metabolise tamoxifen used in the treatment of their breast cancer, according to new research presented at the 22nd EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics … Continue reading

Published Friday, November 19th, 2010 at 12:01 am
Posted in Cancer, Genetics

New drug targets vitamin D receptors in hormone resistant prostate cancers: promising results from first clinical trial

A new anti-cancer drug aimed at vitamin D receptors on cancer cells has prompted encouraging responses in the levels of PSA (prostate specific antigen) in men with prostate cancer that has become resistant to hormonal therapies. Results of the phase … Continue reading

Published Thursday, November 18th, 2010 at 12:01 am
Posted in Cancer

PARP inhibitor, MK-4827, shows anti-tumour activity in first trial in humans

A new drug that targets proteins responsible for helping cancer cells to repair damage to their DNA has shown promising anti-tumour activity in its first trial in humans. Some patients with a range of solid tumours, many of whom had … Continue reading

Published Thursday, November 18th, 2010 at 12:01 am
Posted in Cancer, Genetics

Tiny Trojan horses attack brain cancer cells

Scientists in Germany have developed a way of smuggling an anti-cancer drug past the protective blood-brain barrier and into brain tumours and metastases using a nanocarrier – a tiny capsule specially designed to pass through cell membranes and deliver its … Continue reading

Published Thursday, November 18th, 2010 at 12:01 am
Posted in Cancer

Researchers map the way to personalised treatment for ovarian cancer

Researchers have shown that point mutations – mis-spellings in a single letter of genetic code – that drive the onset and growth of cancer cells can be detected successfully in advanced ovarian cancer using a technique called OncoMap. The finding … Continue reading

Published Wednesday, November 17th, 2010 at 12:01 am
Posted in Cancer, Genetics

Personalised medicine: tumour analysis reveals new opportunities for existing cancer drugs

Targeted cancer therapies such as trastuzumab (Herceptin), gefitinib (Iressa) and erlotinib (Tarceva) could be used to treat a wider range of cancers than previously thought, according to new research presented today (Wednesday) at the 22nd EORTC-NCI-AACR [1] Symposium on Molecular … Continue reading

Published Wednesday, November 17th, 2010 at 12:01 am
Posted in Cancer, Genetics

Scientists identify potential new target for treating triple negative breast cancer

Scientists believe they may have found a new target for treating triple negative breast cancer – one of the more difficult breast cancers to treat successfully and for which there is no targeted therapy at present. Triple negative breast cancer … Continue reading

Published Wednesday, November 17th, 2010 at 12:00 am
Posted in Cancer

Use of mild painkillers in pregnancy is associated with an increased risk of male reproductive problems

New evidence has emerged that the use of mild painkillers such as paracetamol, aspirin and ibuprofen, may be part of the reason for the increase in male reproductive disorders in recent decades. Research published in Europe’s leading reproductive medicine journal … Continue reading

Published Monday, November 8th, 2010 at 1:24 pm
Posted in Fertility

Parental infertility and cerebral palsy in children born spontaneously or after IVF/ICSI

Doctors have known for some time that children born after fertility treatments such as in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) are at increased risk of cerebral palsy. However, it was not known whether this risk was due … Continue reading

Published Wednesday, November 3rd, 2010 at 12:05 am
Posted in Fertility
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